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The orientation table below is unpacked, with citations, in the sections that follow

Topiramate attenuates dural vasodilation primarily by inhibiting nitric oxide-mediated release of CGRP from preganglionic fibers of the trigeminal nerve ( 5 The relationship between migraine, oxidative stress, and neurogenic inflammation According to the theory of migraine genesis, the majority of migraine triggers have the ability to cause oxidative stress in the body

Additional details are in Supplementary Methods

BBB-permeable HGF/BDNF mimetic that drives synapse formation, rescues memory in AD and TBI models, and shows an 812-day half-life for convenient daily use