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FMT, as an emerging therapeutic strategy, involves transplanting fecal microbes from healthy donors into the recipient's intestines to modulate microbial and immune balance, offering a novel treatment approach for autoimmune diseases such as SLE [74]

Three studies have shown that GSH:GSSG is lower in children with autism spectrum disorders [85, 87, 91] lending credence to the original findings

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This activation is associated with elevated mitochondrial reactive oxygen species (mtROS), which can trigger the mitochondrial localization and pore-forming activity of GSDMD, thereby facilitating a transition from apoptotic to necroptotic cell death