cycling on and off glp-1 REPEATED USE MAY PROMOTE LONG TERM WEIGHT GAIN: A new mice study found exactly that. Repeated cycles of GLP-1's may have long term adverse effects the very thing they were Cycling for Weight Loss: GLP-1s

Study authors also noted the risk reductions were more pronounced in the cohorts with psoriasis than in those with obesity or diabetes without psoriasis, and that findings were consistent across all sensitivity analyses. Study authors concluded that GLP-1 receptor agonists should be considered for patients with psoriasis and comorbid obesity or diabetes.

2012;7(4):e34608

doi: 10.1080/19490976.2017.1405209 74 LiJ.LinS.VanhoutteP

Bottom Line: Electrolytes Can Help, But Use Them for the Right Reason Electrolyte supplements while using GLP-1 medications can be helpful, especially when your food and fluid intake are low, you are sweating heavily, you are recovering from diarrhea or vomiting, or you feel headachey, weak, lightheaded, or dehydrated