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An open-label study (n=42) found that IV NAC (50 mg/kg) combined with oral NAC (500 mg twice daily) for 3 months increased brain glutathione levels (measured by MRS), increased dopamine transporter binding (measured by DaTscan), and improved UPDRS motor scores (Monti et al., PLoS One, 2016) [53]

[170] Healthcare providers should regularly reassess the need for continued treatment and consider periodic drug holidays to evaluate ongoing necessity

The FDA committee also voted to reclassify TB-500: TB-500 is another peptide primarily used for wound healing, though the FDA noted that it's marketed for at least 14 other health concerns, like hair loss, blood clots and dry-eye disorder

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