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Sin embargo, estas dosis elevadas provocan un aumento importante en la tasa de eventos adversos gastrointestinales (71% para 16 mg frente a 47% para 2 mg) y ms abandonos del tratamiento (18-23% para 8 y 16 mg frente a 7% para 2 mg)

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Clinical studies have demonstrated its efficacy in patients with recurrent metastatic nasopharyngeal carcinoma

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