While these drugs may have ways of working, they serve similar purposes
Mojca Jensterle, from the University Medical Center Ljubljana, explains: "The combined action of both pharmacotherapies, GLP-1 and metformin, may be more effective than the individual action of each drug for the treatment of the metabolic and reproductive disturbances linked to PCOS and may even improve metabolic outcomes in women who previously exhibited deficient responses to metformin." Mojca Jensterle, Department of Endocrinology, University Medical Center Ljubljana Interestingly, metformin has the ability to enhance the bodys natural GLP-1 levels, which might allow for lower doses of GLP-1 receptor agonists without sacrificing results
The healthcare provider may also consider whether a gradual tapering off of Saxenda before starting Wegovy is appropriate or whether it's safe to switch directly from one to the other
Conclusion Aujourdhui, les mdecins ont souvent recours une combinaison de mthodes, mais les modifications sur le mode de vie restent fondamentales et le socle commun de toutes ces mthodes