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In 2024, a study by Schmitt et al., involving a significantly larger cohort of 2023 participants, confirmed that smokers ( n = 418) exhibited higher levels of circulating eryptotic erythrocytes compared to non-smokers ( n = 1000) and ex-smokers ( n = 605) [441]

No published research characterizes adverse events at sustained injectable doses above 5-10 mg/week in humans