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An interesting study compared the gene expression of the invasive MC58 strain and the 522 carrier strain under ex vivo conditions simulating the commensal and virulence compartments to assess the strain-specific impact of gene regulation on meningococcal virulence ( ex vivo phenotypes

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Opioids can reduce peristalsis in humans, 96 but having evacuated the bowel, the pain relief is more important than this transient effect