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Unexplained weight loss that exceeds expected targets, difficulty swallowing, or persistent gastrointestinal symptoms lasting beyond the initial dose-escalation period should also be discussed with your healthcare provider

Earlier Phase 2 Data and Wider Programme The new TRIUMPH-1 results build on earlier Phase 2 data published in The New England Journal of Medicine , which showed an average weight loss of around 24.2% at 48 weeks in adults with obesity

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doi: 10.1111/j.1432-1033.1997.00001.x