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visualized their spatial distribution in both luminal and glandular epithelium using RNA in situ hybridization (RNAscope) and protein immunostaining with antibodies against the newly identified cilia-associated markers ( C11orf88 , C20orf85 , FAM183A and CDHR3) , and further enriched the list of specific markers for the ciliated epithelial cells ( PIFO , FOXJ1 , TPPP3 , TP73 , C11orf88 , C20orf85 , FAM183A , CDHR3 ) (Fig

The restaurants clientele largely consists of upper-income consumers, who tend to have greater access to such treatments

Notably, the SVM provided the overall best performance for our dataset because it is a machine learning approach for binary classification and can handle the smaller datasets well (54)

Subsequently, these changes further activated the downstream NF-kB signaling pathway, ultimately promoting the expression of PD-L1 [170]