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There is also a trial specifically testing whether retatrutide prevents heart attacks and strokes (TRIUMPH-3, 1,800 people), and a head-to-head trial comparing retatrutide directly against tirzepatide (the active ingredient in Zepbound) under identical conditions (NCT06662383, 800 patients)

The safety, pharmacokinetics, and pharmacodynamics of several weekly doses of LY3437943 in persons with type 2 diabetes were examined in a phase 1b experiment

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