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CTS is most common in females aged between 40-60 years old and individuals with diabetes mellitus other risk factors for are: Overloading the wrist and/or fingers Previous wrist fracture or injury Pregnancy Arthritis CTS is characterised by gradual onset of pain into the palm side of the wrist and numbness or paraesthesia (tingling or pins and needles) into the thumb, index finger, middle finger and the inner half of the ring finger (pictured below)