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Bajaj JS, Heuman DM, Sterling RK, et al

The newly discovered conjunctive use of GLP-1RA can improve clinical outcomes in patients with multiple chronic illnesses that have overlapping pathophysiology and help improve quality of life with early introduction

Importantly a methyl block or methyl trapping can be a major cause of anxiety, depression, headaches, migraines and the like because methylfolate is being trapped and not able to be incorporated into the methionine cycle for use

Severe diarrhea can lead to dehydration