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In HeLa cells, GPX8 is enriched in mitochondria-associated membranes (MAMs), a critical integrating center for calcium, lipid metabolism, and redox signaling homeostasis

540,541 More than 25 gene mutations have been reported to be closely related to ALS, of which C9orf72 repetitive amplification mutations and SOD1 mutations are the most common causes

, Wu, S