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Affecting approximately 50% of patients with diabetes, DN is predominantly characterized by distal symmetric polyneuropathy, leading to sensory loss, pain, and motor dysfunction, often resulting in diabetic foot ulcers and lower-limb amputations

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At 32.99% deferred interest, a $2,400 balance left unpaid for even one day past the promotional period generates $800+ in retroactive interest

Spironolactone's protective effects extend to preserving cardiac function, as evidenced by improved left ventricular ejection fraction and fractional shortening in treated rats [171]