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SARS-CoV-2 infected patients demonstrate a wide spectrum of cutaneous manifestations, including maculopapular or perifollicular rash, urticaria, vesicles, petechiae, purpura, livedo racemosa, and pseudo-chilblains, often referred to as the COVID toes 263,264

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These in vitro observations not only provide an initial basis for in vivo treatment regimens focusing on the stimulation of endogenous hepatic glutathione levels, but could also contribute to an optimization of treatment intervals to limit the risk of adverse effects when NFT is administered as an antibiotic