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While promising preliminary data suggest GHK-Cu may support collagen synthesis and foster tissue repair

(c) Genes that are differentially expressed with TGF treatment or that are down-regulated with increasing emphysema severity are enriched among genes that change in expression with GHK (10 nM) in fibroblast cell lines

ROS can reduce endothelial barrier function, facilitating lipoprotein deposition and oxidative modification of low-density lipoprotein (LDL) particles in the vessel wall [104]