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The MD simulations described above included the G s heterotrimer and revealed that the receptor-G s interactions were very similar regardless of the bound agonist, albeit the majority of interactions were transient (Figure 8B, Supplemental Figure 13, Supplemental Tables 4-5)
The half-life of elimination is about 1.6 hours after intravenous administration
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352 In LPS/IFN--induced inflammation models, lipid peroxidation levels are increased, and GPX4 expression is significantly reduced, promoting ferroptosis in intestinal epithelial cells
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