Smoking habit is the principal risk factor for both emphysema and LC, something that suggests the existence of common disease development pathways (7)
Regardless of the cause, untreated limb length inequalities underlie many painful musculoskeletal problems in adults [37,47] including lower back pain [48,49], gait abnormalities [5054], scoliosis (abnormal curvature of the spine) [55], and osteoarthritis of the hip and knee [5659]
Under the MHRA's 'borderline products' guidance, transdermal patches designed to deliver active substances systemically would typically be classified as medicines requiring marketing authorisation
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