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Weekly dosage schedule Starting dose: 0.25 mg weekly for first 4 weeks Titration phase: 0.5 mg weekly for 4 weeks and then, if tolerated, 1 mg weekly for 4 weeks Maintenance dose for long-term weight management: 1.7 mg once weekly for 4 weeks and then, if tolerated, 2.4 mg once weekly (maximum dose) Dosing considerations If you do not tolerate dose escalation, consult with your healthcare provider and consider delaying the dose escalation for at least 4 weeks

doi: 10.1038/s41579-023-00904-3 15

Adequate fluid intakeat least 64 ounces dailyis crucial for preventing and treating constipation

Support Healthy Homocysteine Levels