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Tea I, De Luca A, Schiphorst AM, Grand M, Barill-Nion S, Miralli E, Tcherkez G (2021) Stable isotope abundance and fractionation in human diseases

235 Additionally, the oxidation of guanosine to 8-oxo-2-deoxyguanosine (8-oxodG) at CpG sites directly interferes with methylation

BPA is another example of a xenoestrogen with pleiotropic effects dependent on AR status, as it promotes the activation of AR-T877A, leading to androgen-independent PCa cell proliferation [292]