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Many providers use Tesofensine as an add-on rather than a replacement because it helps increase energy expenditure while the GLP-1 continues appetite regulation

10.1016/j.redox.2020.101702 [DOI] [PMC free article] [PubMed] [Google Scholar] Liu S, Liu J, Wang Y, Deng F, Deng Z (2025) Oxidative stress: signaling pathways, biological functions, and disease

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