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408 Studies have shown that the loss of GLP-1R in astrocytes can impair mitochondrial integrity, leading to the dysfunction and inhibition of glucose uptake and -oxidation

Moreover, the rise in off-label use fueled by social media and societal pressures around body image underscores the importance of seeking guidance from healthcare professionals and relying on accurate information

However, upper small intestinal activation of protein kinase A (PKA) bypasses CCK resistance in regulating glucose homeostasis, although the role of PKA in feeding regulation remains unclear 196