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The syringe materials (typically polypropylene or cyclic olefin polymer) may interact differently with the peptide than glass, and the air-liquid interface in a pre-filled syringe is less favorable than in a properly filled vial

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The 7.2 mg dose was approved to help patients achieve deeper weight reductionproducing nearly 20% total weight loss in the STEP UP clinical trialsputting its efficacy much closer to that of tirzepatide