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[18] [19] Patients should be instructed to report emergent suicidal thoughts or behaviors, and the medication should be discontinued if these occur

Emerging evidence also points to the benefits of oral prebiotics such as xylitol, arginine, and dietary nitrate, and oral-specific probiotics as adjunctive tools

This combination represents the most widely studied GH secretagogue pairing, based on the well-characterized synergistic interaction between GHRH and GHSR signaling at the pituitary level

Liting Jiang, [email protected] These authors have contributed equally to this work and share the first authorship Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers