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doi: 10.1016/j.eplepsyres.2020.106280 26 KeglerAPascotiniETCapraraALFArendJGabbiPDuarteMMet al

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It also inhibits MPTP-induced oxidative stress in the substantia nigra of subacute Parkinsons mice by regulating the Nrf2/HO-1/NAD(P)H:quinone oxidoreductase 1 (NQO1) signaling pathway, thus preventing dopaminergic neuron apoptosis and improving both exercise ability and anxiety behavior in mice (Wang et al., 2020

This is most relevant at the thigh and abdomen in lean patients