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Although not directly related to inflammation due to a physiologic change in the microenvironment, GLP-1RAs have the potential to replace current standard of care treatment for IIH and can ultimately contribute to improved patient outcomes in the field of neuro-ophthalmology

Recruitment of GSH into these compartments suggests the presence of proteins that can increase the permeability of pores for GSH sequestration in the nucleus and mitochondria as is observed for animal cells [46,164]

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Meanwhile, the outer membrane will rupture, and proteins, such as cytochrome c and apoptosis-inducing factor (AIF), will be released from the intermembrane space into the cytosol, triggering apoptosis [190, 191]