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To identify biologically coherent expression patterns within these differentially expressed proteins (DEPs), we performed unsupervised hierarchical clustering analysis, which revealed two distinct protein clusters with consistent expression trends across samples: 8 upregulated and 7 downregulated proteins (Fig

HSS Journal (2025) 2

In summary, the kinetic data for the E170X mutants support a glutaredoxin-catalysed formation of GSSEtOH as well as an exclusive interaction between Glu170 and the glutathione moiety of GSSR in accordance with the glutathione-scaffold model

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