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Description

Subjects were in a seated position during the first 2 h after dosing

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These findings underscore that GIP agonism and antagonism represent two distinct, context-dependent strategiesthe former enhancing insulin secretion and metabolic flexibility under physiological stimulation, and the latter mitigating GIPR overstimulation in obesity-associated insulin resistance [42,47]

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doi: 10.1097/EDE.0b013e3181c1592b 74 PearceENLazarusJHMoreno-ReyesRZimmermannMB

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however, this goes beyond the major focus of this review and will not be discussed in detail here

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