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It likely reflect the microbes they have in their gut. But ultimately, he says, while short-term studies looking at the impact of fibers on short chain fatty acid production or the second meal effect* are valuable, the only real test of whether these ingredients amount to Natures Ozempic is looking at clinical endpoints, whether its weight loss, or insulin sensitivity, for example. *the ability of a food to impact consumption at a subsequent meal later in the day or the following day