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Liu C, Wu T, Ren N (2023) Glucagon-like peptide-1 receptor agonists for the management of diabetic peripheral neuropathy

The mechanisms underlying these benefits remain unclear but may relate to metabolic improvements, anti-inflammatory effects, or better overall disease control

The development of depression-like behavior is consolidated by IL-6-induced activation of locus coeruleus neurons and IL-1-induced elevated leptin levels in mice

As of 2026 it remains in clinical trials for obesity, type 2 diabetes, and related conditions, and it has not received FDA approval for any indication