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Mild stomach upset or constipation can occur but usually resolve on their own

4/ Who is an appropriate candidate for GLP-1 agonists for weight loss

Consoli A, Formoso G, Baldassarre MPA, et al

Depending on the agent, the mechanism of action is related to their anticholinergic and calcium channel blocking properties leading to smooth muscle relaxation in the gut (Table 1 gives an overview of the most-described randomized controlled trials (RCTs) assessing the effect of different antispasmodics in approximately 2900 IBS patients