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These data suggest that DHODH inhibition induces ferroptosis in GPX4-low cancer cells while sensitizing GPX4-high cancer cells to ferroptosis

52,53 In DFU, the increasing expression of IL-6 results in a sharp increase in phosphorylated STAT3 levels, 54 which mediates impaired immune cell activation, recruitment, and survival, resulting in delayed wound healing

Metabolic Regulation : Some studies suggest that glutathione may facilitate the metabolic processes that convert vitamin D into its active form, thereby enhancing its efficacy

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