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The availability of oral semaglutide may help to broaden treatment options and facilitate the adoption of earlier treatment with arGLP-1 in the management of DM2
Tirzepatide can reduce oral contraceptive effectiveness, necessitating backup contraception for 4 weeks after starting or increasing doses
Endogenous GLP-1 released from the gut acts directly on vagal afferents, which relay information from the abdomen to the brain and regulate multiple physiological systems
Patients taking diuretics, also called water pills, may need extra monitoring because these medications affect fluid balance
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