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There are no published human clinical trials of Dihexa, and therefore no human safety, toxicology, or pharmacokinetic data
Furthermore, Sun et al., showed that HuSC-Exos protect against kidney ischemia-reperfusion injury by reducing ferroptosis via lncRNA taurine upregulated gene 1, which regulates ACSL4 through serine arginine-rich splicing factor 1 interaction, suggesting a potential acute kidney injury therapy [72, 106] (Table 1)
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500 Additionally, PepGens PGN-EDO51, designed to skip exon 51 in the DMD gene, has shown promising results in Phase I clinical trials and is now in Phase II (NCT06079736)
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