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In the detection of pro-inflammatory factor secretion, we also found that OGD treatment promoted the expression of pro-inflammatory factors, indicating that the inflammatory response was enhanced (Figure 3H)

5 (7), e21.00141

Furthermore, the availability of numerous natural and synthetic Nrf2 inducers isothiocynate (sulforaphan), polyphenols (curcumin and resveratrol), flavonoids (Quercetin and kaempferol), and terpenoids (Carnosic acid) is one of the major advantage for targeting this pathway (Wang et al., 2024)

(PubMed) Maheshwari RK, Singh AK, Gaddipati J, Srimal RC