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www.nature.com

Pocovi-Gerardino G, Correa-Rodrguez M, Callejas-Rubio JL, et al

Among the metabolic genes, follistatin, pyruvate dehydrogenase kinase, isozyme 4, CCAAT/enhancer binding protein beta, phosphorylase kinase regulatory subunit beta, AMP-activated protein kinase, and gamma 3 subunit were significantly upregulated due to synbiotic delivery (125)

Higher temperatures accelerate breakdown and increase impurities