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To evaluate the overall quality of oocytes post-treatment, the researchers analyzed the morphological integrity of oocytes by assessing cytoplasmic fragmentation, a typical indicator of cellular degradation

Biochemical dysfunction Mitochondrial dysfunction Mitochondria are bioenergetic and biosynthetic organelles in the cell, with one of their many roles being the synthesis of cellular ATP via oxidative phosphorylation [88]

Effects of histone deacetylase inhibitor suberoylanikide hydroxamic acid (SAHA) and DNA methylation inhibitor 5-Aza-2deoxycytidine (DAC) on the transcriptional activation of RAR-beta and p21WAF in acute promyelocytic leukemia cells