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Indeed, sustained weight reduction of 15% or more in patients with type 2 diabetes may induce remission in a large proportion of subjects and improve metabolic status in the remaining patients [5]

The GLP-1 compounding market changed significantly in 2025-2026 under FDA enforcement

"We might find some real problems if we are not monitoring the body composition, especially for the older patients," Ahmed says

He led the landmark STEP clinical trials for Novo Nordisk that brought semaglutide to market, co-authored the influential Lancet Commission framework distinguishing clinical from preclinical obesity, and has written multiple books on the subject including a phenotype-based guide for clinicians and the popular Six Factors to Fit