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Together, these effects explain why so many people experience these uncomfortable symptoms when starting these treatments

Even if tirzepatide follows in semaglutides heart healthboosting footsteps, both drugs come with some big caveats

As BED is not only a disorder of appetite but also involves emotional and neurological factors, a holistic treatment approach must consider medication for appetite regulation (for example, GLP1 receptor agonists) alongside local targets in the brains reward systems to address this complex clinical problem

Those findings might explain the reduction of aortic plaques areas independent of body weight changes by semaglutide and liraglutide in this study