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Glutathione has many important functions in our body, but most importantly, it is the king (or queen) of antioxidants, which essentially means that it protects cells (egg/sperm) from damage due to ROS such as lipid hydroperoxides (turning them into alcohols) and hydrogen peroxide (turning it into water)

But the mechanism itself, targeting fat cells directly through a specific receptor pathway, remains scientifically sound and well-characterized

The impact of leucine supplementation on body composition and glucose tolerance following energy restriction: an 8-week RCT in adults at risk of the metabolic syndrome

Both MTX and 7-hydroxy MTX are excreted by the kidneys, and a small part is also excreted in the bile (Reference Saka and Aouacheri2)