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Tirzepatide slows gastric emptying, which changes how quickly and consistently oral pills are absorbed the concern is that pill levels in the bloodstream during those transition windows may be lower than expected, reducing contraceptive efficacy

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Start slowly, use an appropriate concentration, choose a delivery vehicle that works with your skin barrier rather than against it, and be thoughtful about how you layer GHK-Cu with pH-sensitive actives like vitamin C and cell-turnover accelerators like retinol