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Under regular circumstances, GH (growth hormone) binds to its receptor in the liver, and other tissues, and stimulates the synthesis/secretion of IGF-1. In target tissues, the Type 1 IGF receptor, that is homologous to the insulin receptor, is activated by IGF-1, leading to intracellular signaling which stimulates multiple processes leading to statural growth

It is not a single-pathway molecule

Short-term side effects were not observed in this small population, and they did not evaluate if it actually worked for a specific condition or if it was safe for long-term use. Jamie Richardson, BVetMed, head of veterinary medicine at Small Door Veterinary, shares the same concerns