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These controlled micro-injuries trigger the bodys natural wound-healing cascade, prompting a surge in collagen and elastin, the proteins that keep skin firm and smooth

On MyLupusTeam, the social network for people with lupus and their loved ones, people come together to ask questions, give advice, and share their stories with others who understand life with lupus

Specifically, circulating LPS binds to TLR4 on immune cell surfaces, activating the downstream NF-B signaling pathway and promoting the release of pro-inflammatory cytokines such as tumor necrosis factor-alpha (TNF-), interleukin-6 (IL-6), and interleukin-1 beta (IL-1)