Virchows Arch (2019) 474:53950

Contact your GP if you experience: Persistent insomnia lasting more than three months despite implementing sleep hygiene measures, or sooner if it severely affects your daily functioning Severe sleep deprivation that impairs your ability to function safely during daytime activities, particularly if operating machinery or driving Mood changes accompanying sleep disturbance, including persistent low mood, anxiety, or irritability that may indicate depression Impact on quality of life , including inability to work, maintain relationships, or engage in usual activities Seek urgent medical attention if you experience: Chest pain or palpitations during sleep (call 999) Severe breathing difficulties during sleep (call 999) Thoughts of self-harm or suicide (contact your GP urgently, call NHS 111, or 999 in an emergency) Your healthcare provider may conduct a thorough assessment to determine whether the sleep disturbance is related to Wegovy, an underlying condition, or other factors

9 During traditional weight loss methods like dieting alone, it's estimated that lean body mass can account for roughly 20-35% of the total weight lost
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