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The intranasal delivery of quercetin-loaded niosomal in situ gel offers direct central nervous system (CNS) access via the olfactory and trigeminal pathways, minimizing systemic side effects (Gastrointestinal Irritation, Hepatotoxicity, Renal Stress) while enhancing bioavailability

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The science is still unclear, however, as other studies have found that GLP-1 medications can actually increase testosterone levels and improve erectile dysfunction