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Several mechanisms have been proposed, though some remain hypothetical and require further clinical confirmation: Weight reduction : Ozempic typically produces weight loss of approximately 3-6 kg at diabetes doses (0.5-1 mg), which may contribute to reduced cardiovascular strain

Side effects, most often gastrointestinal ones such as nausea, can also prompt a break, especially if they have not settled

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Rising drug budgets are tightening formularies and prior authorization processes, as overall prescription drug spending is expected to increase by 9.0-11.0% in 2025