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Individuals seeking fat loss often have contraindications to growth hormone therapy or prefer to avoid systemic hormonal interventions

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4.2 Mechanism of action of PDEVs 4.2.1 Intercellular communication and signal regulation PDEVs have emerged as a promising candidate for next-generation drug delivery systems, as they can encapsulate and deliver large quantities of bioactive molecules (Zheng et al., 2024

A close relationship between the intracellular localization of proteins and the length and amino acid composition of their TMDs has been reported, and alterations in the TMD also affect the rate of endocytosis 12