Pereira says that medication shortages impacted her patients, who had to switch to less effective drugs, which is especially concerning for patients with diabetes who need the medications to keep their blood glucose in a safe range
These risks include dosing errors, sterility concerns, counterfeit products, altered bioavailability, and reduced clinician oversight in some settings
Clinicians should exercise caution in patients with a history of pancreatitis or gastroparesis, inflammatory bowel disease, other gut motility disorders, medullary thyroid carcinoma, or Multiple Endocrine Neoplasia syndrome type 2, and pause therapy when clinically indicated, such as before anesthesia
Participants with the variants did not respond differently to other common diabetes treatments, including sulfonylureas, metformin and DPP-4i