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Advocates propose that boosting NAD+ could increase energy levels, enhance mitochondrial function, and improve fatigue or cognitive clarity in some individuals

However, most of the current studies focus on diabetic complications related research, revealing the pathophysiological mechanisms of mitophagy in T2DM are relatively few, and need to be further researched

Despite these hurdles, precision targeting of metabolic pathways, interdisciplinary collaboration, and the discovery of novel compoundsparticularly immune-sensitizing agents derived from traditional medicineare expected to accelerate progress